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百蕊片治療反流性咽喉炎的臨床觀察
鐘艷萍,李卡凡,蔡小劍,陳俊曦
(佛山市中醫院,廣東佛山528000)
摘要:目的 探討百蕊片治療反流性咽喉炎的療效。方法 選擇2009 年10 月至2011 年12 月佛山市中醫院耳鼻咽喉科門診診斷為反流性咽喉炎患者共120 例,隨機分為治療組與對照組。對照組口服奧美拉唑,治療組口服奧美拉唑和百蕊片,療程均為8 周。在治療后2 周、4 周、8 周,對兩組進行癥狀和體征評分。結果 治療2 周、4 周、8 周兩組癥狀與體征積分逐漸減少,與治療前比較差異有統計學意義(P < 0.05 或P < 0.01);治療4 周,治療組癥狀、積分療效優于對照組(P < 0.05);治療8 周,治療組癥狀、積分繼續減少,與對照組比較差異有統計學意義(P < 0.01)。結論 在奧美拉唑治療的基礎上,應用百蕊片治療反流性咽喉炎療效明顯,
顯著優于單用奧美拉唑。
關鍵詞:咽喉反流性炎;奧美拉唑;百蕊片
中圖分類號:R285.6 文獻標志碼:A 文章編號:1003-9783(2013)04-0424-03
doi:10.3969/j.issn.1003-9783.2013.04.026
Clinical Observation of Bairui Tablets for Treating Laryngopharyngeal Reflux Disease
ZHONG Yanping,LI Kafan,CAI Xiaojian,CHEN Junxi
(Foshan Hospital of Traditional Chinese Medicine,Foshan528000 Guangdong,China)
Abstract: Objective To explore the effect of Bairui Tablets for the treatment of laryngopharyngeal reflux disease.Methods From October of 2009 to November of 2011,120 cases diagnosed as LPRD from the Otolaryngology department of Foshan Chinese Traditional Medicine Hospital were randomized into treatment group and control group. Thecontrol group was treated by Omeprazole Capsules and the treatment group was treated by Omeprazole Capsules andBairui Tablets orally for 8 weeks. Symptoms and signs were scored in the two groups after treatment for 2,4 and 8 weeks. Results Signs and symptoms scores were gradually reduced after treatment for 2,4 and 8 weeks,the difference being significant compared with those before treatment(P<0.05 or P<0.01). From week 4,the scores of signsand symptoms in treatment group were less than those in control group(P<0.05),and on week 8,the difference being obviously significant(P<0.01). Conclusion Bairui Tablets combined with Omeprazole Capsules is effective for the
treatment of laryngopharyngeal reflux disease,and has better therapeutic effect than Omeprazole Capsules alone.
Keywords:Laryngopharyngeal reflux disease;Omeprazole Capsules;Bairui Tablets
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